There are many different medications that can be used to tackle different the various signaling pathways involved in pain. Many of these medications have been proven to be as effective as opioids for acute pain, especially when combined. Some examples include:
- Acetaminophen (Tylenol ®): There are many applications for this medication that can be used for acute and chronic pain.
- NSAIDS (Ibuprofen, Naproxen): These drugs work by inhibiting pain by targeting the inflammation signaling pathway.
- COX-2 Inhibitors: These drugs inhibit a specific enzyme, which means reduced inflammation. COX-2 inhibitors are commonly used to treat chronic arthritis pain. An example is celecoxib.
- Steroids (Exp: prednisone, dexamethasone): These anti-inflammatory medicines can help reduce acute pain after surgery or injury. They have particular benefit for managing spine and bone pain.
Some medications are particularly useful in the setting of chronic pain. These can include:
- Gabapetanoids (Gabapentin, pregabalin): These drugs reduce inappropriate nerve conduction found in conditions such as diabetic neuropathy and chemotherapy-induced nerve pain.
- Antidepressants: Antidepressant drugs help regulate pain sensations in addition to mood. Antidepressants such as tricyclic antidepressants and serotonin and norepinephrine reuptake inhibitors can be used to treat chronic pain conditions such as fibromyalgia and migraines.
© 1998-2024 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved
Sign up for Updates
To stay up to date please provide your email address.
-
By giving us your email you are opting-in to receive news and promotions
Sign up for Updates
To stay up to date please provide your email address.
-
By giving us your email you are opting-in to receive news and promotions
