Naloxone (Narcan®) is medication that quickly — but only temporarily — reverses an opioid overdose. Naloxone does not reverse an overdose from other medications.

Naloxone is only a temporary solution to an overdose. Naloxone typically works for only 30 to 90 minutes. No matter which method you use to give naloxone, be prepared to give repeated doses if needed while you wait for emergency responders to arrive.